Plasmonic biosensors

Plasmonic biosensors with biocompatible nanosilver

The plasmonic properties of noble metal nanoparticles facilitate their use in novel in-vivo bio-applications such as targeted drug delivery and cancer cell therapy. Nanosilver is best suited for such applications as it has the lowest plasmonic losses among all such materials in the UVvisible spectrum. Its toxicity, however, can destroy the surrounding healthy tissue and thus, hinders its safe e...

3D plasmonic nanoantennas integrated with MEA biosensors.

Neuronal signaling in brain circuits occurs at multiple scales ranging from molecules and cells to large neuronal assemblies. However, current sensing neurotechnologies are not designed for parallel access of signals at multiple scales. With the aim of combining nanoscale molecular sensing with electrical neural activity recordings within large neuronal assemblies, in this work three-dimensiona...

Engineered Metallic Structures and Nanofabrication Techniques for Plasmonic Biosensors

Optical energy can be harnessed on the nanoscale by exploiting plasmonic resonances in metallic nanostructures. These resonances are the result of the unique optical properties of metals and their abundance of conduction electrons. Utilizing these properties, it is possible to engineer metallic nano-devices that operate with large electric field intensities confined in and around the structure....

Detection limits in whispering gallery biosensors with plasmonic enhancement

Ultra-sensitive immunoassay biosensors using hybrid plasmonic-biosilica nanostructured materials.

We experimentally demonstrate an ultra-sensitive immunoassay biosensor using diatom biosilica with self-assembled plasmonic nanoparticles. As the nature-created photonic crystal structures, diatoms have been adopted to enhance surface plasmon resonances of metal nanoparticles on the surfaces of diatom frustules and to increase the sensitivity of surface-enhanced Raman scattering (SERS). In this...